Towards a better detection of Alzheimer's

Towards a better detection of Alzheimer's



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Improved early detection of Alzheimer's
Early diagnosis of Alzheimer's can bring significant benefits for patients. Because the disease has not yet been curable, but its course can be significantly delayed, so that those affected can live their normal everyday lives longer. Professor Michael Ewers from the Ludwig Maximillians University in Munich (LMU) and colleagues have therefore set themselves the goal of improving the early diagnosis of dementia. Your research is supported by project funding from the Alzheimer Research Initiative, according to the LMU.

Years before the appearance of dementia, abnormal changes in the brain show up in Alzheimer's, reports the LMU. These early brain changes could be measured using “high-resolution magnetic resonance imaging (MRI) and other imaging methods.” Neuroscientist Professor Michael Ewers from the Institute for Stroke and Dementia Research at the LMU is an expert in the field. He is researching how changes in brain scan and other early signs of Alzheimer's disease can be used for early detection. His project "Diagnostic procedure for the early detection of Alzheimer's disease" is funded with 80,000 euros by the non-profit Alzheimer Research Initiative.

Recognize Alzheimer's risk profiles
In the meantime, according to the LMU, "with the imaging methods, neuropsychological examinations, and biomarkers from nerve water and blood, an abundance of test methods are available" that can be used for the diagnostic measurement of early cognitive and cerebral changes in Alzheimer's disease. However, the risk profiles typical of Alzheimer's can often be identified here "only in the summary of the results of some important test procedures and used for the diagnosis of individual cases."

Fully automated process for early detection
The research team led by Professor Michael Ewers is trying to derive “algorithms for the early detection of the disease” based on the existing investigation methods, according to the LMU. For this purpose, the results of imaging procedures, neuropsychological or genetic examinations should be brought together. The goal is a fully automated, computer-aided procedure, “so that the risk profile of the disease can be created using as few, but meaningful, tests as possible,” reports the LMU. The aim of their project is to enable doctors to "identify the Alzheimer's risk in their patients as early as possible," explains the university. (fp)

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Video: How to get a diagnosis of dementia?